Sequencing Baby DNA, a Project in Boston

1 Reply Jonny Hankins

Last week the Science in Mind blog on my local Boston.com website ran an interesting story that is definitely worthy of reflection. It involves 2 local hospitals that are carrying out a project funded by the National Institute of Health (USA). The projects involve sequencing the DNA of newly born babies over the next 5 years. Read all about it here.

Babies to have their DNA sequenced

Babies to have their DNA sequenced

Now sequencing the DNA of babies carries with it several risks and ethical concerns, as well as well argued benefits. If we take the benefits first, doctors may gain information about a baby, such as high risk for a certain disease, genetic mutations that may require changes of lifestyle etc. They might also find explanations for problems that might otherwise go undetected.

There are though as I say risks and concerns. How will parents react if they discover that their baby has a high risk of an incurable disease? How will the knowledge gained through the test effect the way the parents view and behave towards their children? Are we giving families information that will change their understanding of parenting to such a degree that it might destroy the very fabric of their social relationships?

This is not to mention the social implications of giving out such information regarding extended family. If for example I am told that my baby has a genetic mutation carried by the parents that might have a serious effect on its life, should I tell my brothers and cousins so that they can screen their prospective wives, make decisions about having children or even worse a pregnancy already in course? And not to mention the obvious problem of discovering that the father is not the man stood in the room with the mother.

These problems are in fact the issues that the researchers running the project are hoping to look into. The question is if the clinical benefits outweigh the risks of such an approach.

I have written a lot about this subject in recent years if you would like more to read:

In June of last year I wrote a post here on Technology Bloggers called Sequencing the Genome of Unborn Babies. I also raised a lot of similar ethical concerns in May of the same year in Home Genetic Testing, Pros and Cons.

On the Bassetti Foundation we find DNA Privacy Issues from January of this year, a series called Architectures for Life from 2012 and a review of a book called Go Ask Your Father, just for starters.

My own personal view is that much of the promise peddled to us surrounding medicine and the sequencing of the human genome has yet to be delivered. One problem is money. Personalized medicine sounds like a great idea. I get my genome sequenced, we can see which drugs might work the best, the type of treatment I need etc. But drug companies cannot make, test and market a drug especially for me even with all of this information, it is just not cost effective. They want big sellers, generic medicines that work to some extent on everybody, not something that is fantastic for me with my particular gene pool.

There are clinical benefits, I am not arguing otherwise, but we must wait to see how great.

Reviewing Mobile Fun’s FlexiShield case for the S4 Mini

2 Replies Christopher Roberts

This is the second article in a series reviewing the Samsung Galaxy S4 Mini.

In this article I will be looking at a FlexiShield case for the Galaxy S4 Mini.

Which Case?

If you browse Mobile Fun’s site, you will see they have a huge range of cases for the S4 Mini, (at the time of writing, they had around 80) so choosing the right case can be a challenge. Different cases have different purposes, so in order to get the right case for you, you need to decide what you want to use it for.

Here are some of the different functions you might want from a case:

  • Protection – probably number one for most people
  • Design – a stylish case can add to the phones aesthetic appeal
  • Storage – some wallet style cases also allow you to store credit cards in the cover
  • Functionality – the Samsung official case lets you access some functions through the window in the screen cover, whilst saving power by not keeping the whole screen on

I want a case which protects my phone and also looks good. Protection is my top priority, as I don’t want to damage my phone, although if I can make it look better in the process, that’s a bonus.

Mobile Fun’s FlexiShield Case Review

The first of the two cases I have chosen to review is Mobile Fun’s own brand FlexiShield case.

Mobile Fun: Galaxy S4 Mini FlexiShield CaseI am going to be honest, I didn’t have high expectations of the FlexiShield case, as I had looked at reviews of a similar case for the S4 Mini’s big brother, (the S4) and they weren’t very positive. This meant that when I received the case and discovered how great it was, I was pleasantly surprised! 🙂

Price

One of the reasons for my initial doubt was the price. The case currently costs less than £10, which is one of the cheapest S4 Mini cases on the market. Samsung’s Official case (which offers very little protection in comparison) costs around £18, so in terms of protection, the FlexiShield one is very competitively priced.

Design

S4 Mini FlexiShield Case chargingThe FlexiShield case is surprisingly durable, as you would expect from the name, the case is quite flexible, yet when it is fitted on the phone it is very strong. The case fits the phone perfectly, and leaves all the vital ports and sensors accessible. The top ports are all perfectly aligned, however access to the camera and bottom microphone, whilst still accessible is slightly off-centre, which looks a little untidy.

My phone is the white version, so I chose the ‘Frost White’ version of the case, and it looks great! The phone is still visible, as the case is semi-transparent.

The power and volume buttons are covered by the case, so all you have to do to access them is push on the side of the case. Similar cases have recesses where the buttons are, making them hard to press, however this is not an issue with the FlexiShield for the S4 Mini.

At times my phone does appear to be overheating when in the case, however this is usually only when it isn’t in a well ventilated area. The phone is fine when I have it in my pocket, just don’t go and wrap it in a blanket!

Sometimes when GPS and mobile data are on and the phone is trying to process something (like mapping) I do notice the back getting hot, so I usually remove it from the case.

Protection
Whilst the FlexiShield can’t offer the same protection that a D3O case can, it does offer a reasonably high level. When fitted on the phone, the case covers all of the back and sides and has a lip which is elevated over the top of the phone, meaning that no matter how the phone falls (proving it is falling onto a flat surface, not a spike or something!) the case will take the impact, not the device itself.

Mobile Fun's Samsung Galaxy S4 Mini FlexiShield CaseRather by accident, I tested the true protection of the case by throwing my phone about a meter across the room, where it came to land on the floor. The thud when it hit the ground wasn’t reassuring, however the case had absorbed the impact, meaning my phone was intact. I wouldn’t advise you thrown it at the floor, however if you do drop/throw it, the case will provide some protection.

The case does a great job of protecting the phone from marks and stains. It is really easy to clean with a damp cloth, and keeps your phone safe from harm.

Rating

Mobile Fun’s own brand case is very competitively priced for what it offers: durable, well designed protection for the S4 Mini.

UPDATE: Having reviewed Tech21’s Impact Shield case I am downgrading this case from 4 star to 3 star.

I rate Mobile Fun’s S4 Mini FlexiShield case three star.Three Star

Next Week

In the next post in the series I will be reviewing Tech21’s Impact Shield case for the S4 Mini. See you then. 🙂

Facebook Addiction?

11 Replies Jonny Hankins

Do you ever feel that Facebook has got the better of you? That it has some kind of force that draws you in every time you go near your computer? Well if so you should know that you are not alone.

Two researchers here at MIT have conducted some experiments to see if they could halt their addiction in its tracks. The researchers put some code into their machines that monitors the sites they visit through their browser. When they visit Facebook too often an electric shock is sent through a peripheral device to their keyboard, and they get a jolt.

Now if you have ever spent any time with cows you will know that they respect electric fences because they hurt, and the researchers think that this system might deter them from too much use. They call it Pavlov’s Poke.

And surely enough after a few shocks the boys used Facebook a little less.

Thumbs down.

Thumbs down to Facebook overuse.

There is also the story of a young man who hired a woman through our local newspaper to help him avoid Internet distraction. She sat next to him in his office and slapped him in the face when he lost the thread of his searches. Probably a little cumbersome as a solution though, not to mention pricey. Read the story here.

So the boys came up with an automated version that posts a job request through Amazon’s Mechanical Turk service when the quota is reached. The job requires a person to call and abuse you reading from a script, simple and a much better use of human resources I would think.

And we might really be talking about addiction here. A study cited in Forbes by the University of Chicago claims that Facebook is more addictive than cigarettes or alcohol, with the average user spending 400 minutes a month on the site.

Another report from the University of Utah shows that people who use Facebook a lot are led to believe that other people’s lives are better than theirs.

This is an easy conclusion to come to when you look at photos of your friends (and people you don’t really know or never really speak to face to face) while they are on holiday, having fun in clubs, meeting new people and going to music festivals, while you are sitting at home in front of your computer feeling miserable. Photos of arguing with your partner or the kids waking up at 4 in the morning are rarer.

Researchers at the University of Michigan came to the same conclusion. Read their report in full here. This is a brand new piece of research.

The truth is that these social media sites are designed to be both addictive and necessary. They make you feel better in some ways, people of course like you, but they distort views of real life and can lead to distraction and unhappiness.

They make money by selling, so they need as many online presences as they can get and for as long and often as possible. They are (as they openly admit) marketplaces, designed to sell access to their users for publicity purposes. They are not apolitical and have goals, and their success makes or breaks their share price.

On a personal note I recently applied for a job in the USA as a freelance journalist. Although I have lots of experience, good qualifications and a measurable reader base, I got no further than the application form. The employers wanted details of my social network, Facebook, Google plus etc, not my writing.

I had nothing to offer them.